PISA involves all partners interested in controlling animal health, including the Government (or department responsible for a specific area), farm producer associations and respective farms.
PISA.net includes the whole hierarchy of veterinary administrators, on-site veterinary surgeons and laboratories responsible for analysing animal samples collected.

It works online, from any PC connected to the central database, or offline, through a local database intelligently synchronized with the central database, which responds to the availability of a communication channel.
Thus, the system is used and handled from different regional, national, continental or global points on the animal health control network, in offices or on-site. Users are situated in different geographic locations, so The system's main objective is to register, process and supply all information entered and updated by each individual or authorised organism, in accordance with their duties and permission. This is all done using a central database.